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BMC Pulm Med ; 21(1): 267, 2021 Aug 17.
Artículo en Inglés | MEDLINE | ID: covidwho-1362053

RESUMEN

BACKGROUND: The aim of the study is to estimate the prevalence of atelectasis assessed with computer tomography (CT) in SARS-CoV-2 pneumonia and the relationship between the amount of atelectasis with oxygenation impairment, Intensive Care Unit admission rate and the length of in-hospital stay. PATIENTS AND METHODS: Two-hundred thirty-seven patients admitted to the hospital with SARS-CoV-2 pneumonia diagnosed by clinical, radiology and molecular tests in the nasopharyngeal swab who underwent a chest computed tomography because of a respiratory worsening from Apr 1 to Apr 30, 2020 were included in the study. Patients were divided into three groups depending on the presence and amount of atelectasis at the computed tomography: no atelectasis, small atelectasis (< 5% of the estimated lung volume) or large atelectasis (> 5% of the estimated lung volume). In all patients, clinical severity, oxygen-therapy need, Intensive Care Unit admission rate, the length of in-hospital stay and in-hospital mortality data were collected. RESULTS: Thirty patients (19%) showed small atelectasis while eight patients (5%) showed large atelectasis. One hundred and seventeen patients (76%) did not show atelectasis. Patients with large atelectasis compared to patients with small atelectasis had lower SatO2/FiO2 (182 vs 411 respectively, p = 0.01), needed more days of oxygen therapy (20 vs 5 days respectively, p = 0,02), more frequently Intensive Care Unit admission (75% vs 7% respectively, p < 0.01) and a longer period of hospitalization (40 vs 14 days respectively p < 0.01). CONCLUSION: In patients with SARS-CoV-2 pneumonia, atelectasis might appear in up to 24% of patients and the presence of larger amount of atelectasis is associated with worse oxygenation and clinical outcome.


Asunto(s)
COVID-19 , Hipoxia , Neumonía Viral , Atelectasia Pulmonar , Tomografía Computarizada por Rayos X/métodos , Anciano , COVID-19/diagnóstico , COVID-19/mortalidad , COVID-19/fisiopatología , Prueba de COVID-19/métodos , Femenino , Humanos , Hipoxia/etiología , Hipoxia/terapia , Unidades de Cuidados Intensivos/estadística & datos numéricos , Tiempo de Internación/estadística & datos numéricos , Pulmón/diagnóstico por imagen , Mediciones del Volumen Pulmonar/métodos , Masculino , Neumonía Viral/diagnóstico por imagen , Neumonía Viral/etiología , Neumonía Viral/fisiopatología , Neumonía Viral/terapia , Prevalencia , Atelectasia Pulmonar/diagnóstico por imagen , Atelectasia Pulmonar/epidemiología , Atelectasia Pulmonar/etiología , Atelectasia Pulmonar/fisiopatología , Respiración Artificial/métodos , Respiración Artificial/estadística & datos numéricos , Estudios Retrospectivos , SARS-CoV-2/aislamiento & purificación , Índice de Severidad de la Enfermedad , España/epidemiología , Tomografía Computarizada por Rayos X/estadística & datos numéricos
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